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BL-038, a Benzofuran Derivative, Induces Cell Apoptosis in Human Chondrosarcoma Cells through Reactive Oxygen Species/Mitochondrial Dysfunction and the Caspases Dependent Pathway
Chondrosarcoma is a highly malignant cartilage-forming bone tumor that has the capacity to invade locally and cause distant metastasis. Moreover, chondrosarcoma is intrinsically resistant to conventional chemotherapy or radiotherapy. The novel benzofuran derivative, BL-038 (2-amino-3-(2,6-dichloroph...
Autores principales: | Liu, Ju-Fang, Chen, Chien-Yu, Chen, Hsien-Te, Chang, Chih-Shiang, Tang, Chih-Hsin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037769/ https://www.ncbi.nlm.nih.gov/pubmed/27618007 http://dx.doi.org/10.3390/ijms17091491 |
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