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Biased and Unbiased Methods for the Detection of Off-Target Cleavage by CRISPR/Cas9: An Overview

The clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 9 endonuclease (Cas9) derived from bacterial adaptive immune systems is a revolutionary tool used in both basic and applied science. It is a versatile system that enables the genome of different species to be mo...

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Detalles Bibliográficos
Autores principales:	Martin, Francisco, Sánchez-Hernández, Sabina, Gutiérrez-Guerrero, Alejandra, Pinedo-Gomez, Javier, Benabdellah, Karim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037784/ https://www.ncbi.nlm.nih.gov/pubmed/27618019 http://dx.doi.org/10.3390/ijms17091507

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