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A Protocol to Enhance INS1E and MIN6 Functionality—The Use of Theophylline

In vitro research in the field of type I diabetes is frequently limited by the availability of a functional model for islets of Langerhans. This method shows that by the addition of theophylline to the glucose buffers, mouse insulinoma MIN6 and rat insulinoma INS1E pseudo-islets can serve as a model...

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Detalles Bibliográficos
Autores principales: Groot Nibbelink, Milou, Marchioli, Giulia, Moroni, Lorenzo, Karperien, Marcel, Van Apeldoorn, Aart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037807/
https://www.ncbi.nlm.nih.gov/pubmed/27626415
http://dx.doi.org/10.3390/ijms17091532

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