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A Protocol to Enhance INS1E and MIN6 Functionality—The Use of Theophylline
In vitro research in the field of type I diabetes is frequently limited by the availability of a functional model for islets of Langerhans. This method shows that by the addition of theophylline to the glucose buffers, mouse insulinoma MIN6 and rat insulinoma INS1E pseudo-islets can serve as a model...
Autores principales: | Groot Nibbelink, Milou, Marchioli, Giulia, Moroni, Lorenzo, Karperien, Marcel, Van Apeldoorn, Aart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037807/ https://www.ncbi.nlm.nih.gov/pubmed/27626415 http://dx.doi.org/10.3390/ijms17091532 |
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