Cargando…

Alterations in Serum Polyunsaturated Fatty Acids and Eicosanoids in Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)

Smoking is a major risk factor for several diseases including chronic obstructive pulmonary disease (COPD). To better understand the systemic effects of cigarette smoke exposure and mild to moderate COPD—and to support future biomarker development—we profiled the serum lipidomes of healthy smokers,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Titz, Bjoern, Luettich, Karsta, Leroy, Patrice, Boue, Stephanie, Vuillaume, Gregory, Vihervaara, Terhi, Ekroos, Kim, Martin, Florian, Peitsch, Manuel C., Hoeng, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037848/ https://www.ncbi.nlm.nih.gov/pubmed/27657052 http://dx.doi.org/10.3390/ijms17091583

Ejemplares similares

Physiological and biological characterization of smokers with and without COPD
por: Chaudhary, Nveed, et al.
Publicado: (2018)

Mechanistic Evaluation of the Impact of Smoking and Chronic Obstructive Pulmonary Disease on the Nasal Epithelium
por: Talikka, Marja, et al.
Publicado: (2017)

Reduced Chronic Toxicity and Carcinogenicity in A/J Mice in Response to Life-Time Exposure to Aerosol From a Heated Tobacco Product Compared With Cigarette Smoke
por: Wong, Ee Tsin, et al.
Publicado: (2020)

Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe(−/−) Mice—An Integrative Systems Toxicology Analysis
por: Titz, Bjoern, et al.
Publicado: (2016)

Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice
por: Titz, Bjoern, et al.
Publicado: (2020)

Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice
por: Ansari, Sam, et al.
Publicado: (2016)

Proteomics and Lipidomics in Inflammatory Bowel Disease Research: From Mechanistic Insights to Biomarker Identification
por: Titz, Bjoern, et al.
Publicado: (2018)

Effects of cigarette smoke exposure on a mouse model of multiple sclerosis
por: Ho, Jenny, et al.
Publicado: (2022)

Construction of a Suite of Computable Biological Network Models Focused on Mucociliary Clearance in the Respiratory Tract
por: Yepiskoposyan, Hasmik, et al.
Publicado: (2019)

Comparing the preclinical risk profile of inhalable candidate and potential candidate modified risk tobacco products: A bridging use case
por: Schlage, Walter K., et al.
Publicado: (2020)

Comparison of the basic morphology and function of 3D lung epithelial cultures derived from several donors
por: Bovard, David, et al.
Publicado: (2020)

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe(−/−) Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes
por: Phillips, Blaine, et al.
Publicado: (2016)

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe(−/−) Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes
por: Phillips, Blaine, et al.
Publicado: (2016)

Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model
por: Luettich, Karsta, et al.
Publicado: (2014)

Retraction: TGFβ(1 )activates c-Jun and Erk1 via a(V)β(6 )integrin
por: Luettich, Karsta, et al.
Publicado: (2004)

TGFβ(1 )activates c-Jun and Erk1 via α(V)β(6 )integrin
por: Luettich, Karsta, et al.
Publicado: (2003)

Hyperhomocysteinemia dysregulates plasma levels of polyunsaturated fatty acids-derived eicosanoids
por: Al-Shabrawey, Mohamed, et al.
Publicado: (2022)

Eicosanoids and Eosinophilic Inflammation of Airways in Stable COPD
por: Celejewska-Wójcik, Natalia, et al.
Publicado: (2021)

Development of an Advanced Multicellular Intestinal Model for Assessing Immunomodulatory Properties of Anti-Inflammatory Compounds
por: Marescotti, Diego, et al.
Publicado: (2021)

Changes in erythrocyte polyunsaturated fatty acids and plasma eicosanoids level in patients with asthma
por: Zhou, Jing, et al.
Publicado: (2018)

Proteomics for systems toxicology
por: Titz, Bjoern, et al.
Publicado: (2014)

Polyunsaturated fatty acids alter the formation of lipid droplets and eicosanoid production in Leishmania promastigotes
por: Andrade, Yasmin Monara Ferreira de Sousa, et al.
Publicado: (2023)

Evaluation of toxicity of aerosols from flavored e-liquids in Sprague–Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis
por: Ho, Jenny, et al.
Publicado: (2020)

Differential action of polyunsaturated fatty acids and eicosanoids on bleomycin-induced cytotoxicity to neuroblastoma cells and lymphocytes
por: Polavarapu, Sailaja, et al.
Publicado: (2017)

Embracing Transparency Through Data Sharing
por: Boué, Stéphanie, et al.
Publicado: (2018)

Lung cancer biomarkers for the assessment of modified risk tobacco products: an oxidative stress perspective
por: Lowe, Frazer J., et al.
Publicado: (2013)

Assessment of inhalation toxicity of cigarette smoke and aerosols from flavor mixtures: 5‐week study in A/J mice
por: Wong, Ee Tsin, et al.
Publicado: (2022)

Eicosanoids metabolized through LOX distinguish asthma–COPD overlap from COPD by metabolomics study
por: Cai, Chuanxu, et al.
Publicado: (2019)

Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke
por: Titz, Bjoern, et al.
Publicado: (2020)

Rhinosinusitis in COPD: symptoms, mucosal changes, nasal lavage cells and eicosanoids
por: Piotrowska, Violetta M, et al.
Publicado: (2010)

Multi-level immune response network in mild-moderate Chronic Obstructive Pulmonary Disease (COPD)
por: Cruz, Tamara, et al.
Publicado: (2019)

Dyspnoea and symptom burden in mild–moderate COPD: the Canadian Cohort Obstructive Lung Disease Study
por: Cherian, Mathew, et al.
Publicado: (2021)

Mitochondria as a possible target for nicotine action
por: Malińska, Dominika, et al.
Publicado: (2019)

First anniversary of Molecular Cancer: achievements and future goals
por: Deora, Arun B, et al.
Publicado: (2003)

The association of eicosanoids and eicosanoid-related metabolites with pulmonary hypertension
por: McNeill, Jenna N., et al.
Publicado: (2023)

A 6-month inhalation toxicology study in Apoe(−/−) mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract
por: Wong, Ee Tsin, et al.
Publicado: (2021)

The Apoe(−/−) mouse model: a suitable model to study cardiovascular and respiratory diseases in the context of cigarette smoke exposure and harm reduction
por: Lo Sasso, Giuseppe, et al.
Publicado: (2016)

Heterogeneity in the respiratory symptoms of patients with mild-to-moderate COPD
por: Johnson, Kate M, et al.
Publicado: (2018)

Factors associated with exacerbation in mild- to-moderate COPD patients
por: Kim, Joo Kyung, et al.
Publicado: (2016)

Lipidomic profiling of patient-specific iPSC-derived hepatocyte-like cells
por: Kiamehr, Mostafa, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_hh6cpqgabtnhjrj19qtralo7ht