Anthocyanin Attenuates Doxorubicin-Induced Cardiomyotoxicity via Estrogen Receptor-α/β and Stabilizes HSF1 to Inhibit the IGF-IIR Apoptotic Pathway

Doxorubicin (Dox) is extensively used for chemotherapy in different types of cancer, but its use is limited to because of its cardiotoxicity. Our previous studies found that doxorubicin-induced insulin-like growth factor II receptor (IGF-IIR) accumulation causes cardiomyocytes apoptosis via down-reg...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Pei-Chen, Kuo, Wei-Wen, Shen, Chia-Yao, Chen, Yu-Feng, Lin, Yueh-Min, Ho, Tsung-Jung, Padma, V. Vijaya, Lo, Jeng-Fan, Huang, Chih-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037853/
https://www.ncbi.nlm.nih.gov/pubmed/27657062
http://dx.doi.org/10.3390/ijms17091588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037853/
https://www.ncbi.nlm.nih.gov/pubmed/27657062
http://dx.doi.org/10.3390/ijms17091588

Ejemplares similares