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Involvement of Ca(2+) Signaling in the Synergistic Effects between Muscarinic Receptor Antagonists and β(2)-Adrenoceptor Agonists in Airway Smooth Muscle
Long-acting muscarinic antagonists (LAMAs) and short-acting β(2)-adrenoceptor agonists (SABAs) play important roles in remedy for COPD. To propel a translational research for development of bronchodilator therapy, synergistic effects between SABAs with LAMAs were examined focused on Ca(2+) signaling...
Autores principales: | Fukunaga, Kentaro, Kume, Hiroaki, Oguma, Tetsuya, Shigemori, Wataru, Tohda, Yuji, Ogawa, Emiko, Nakano, Yasutaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037855/ https://www.ncbi.nlm.nih.gov/pubmed/27657061 http://dx.doi.org/10.3390/ijms17091590 |
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