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OX133, a monoclonal antibody recognizing protein-bound N-ethylmaleimide for the identification of reduced disulfide bonds in proteins

In vivo, enzymatic reduction of some protein disulfide bonds, allosteric disulfide bonds, provides an important level of structural and functional regulation. The free cysteine residues generated can be labeled by maleimide reagents, including biotin derivatives, allowing the reduced protein to be d...

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Detalles Bibliográficos
Autores principales: Holbrook, Lisa-Marie, Kwong, Lai-Shan, Metcalfe, Clive L., Fenouillet, Emmanuel, Jones, Ian M., Barclay, A. Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037987/
https://www.ncbi.nlm.nih.gov/pubmed/26986548
http://dx.doi.org/10.1080/19420862.2016.1152443