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Generation, characterization and preclinical studies of a human anti-L1CAM monoclonal antibody that cross-reacts with rodent L1CAM

L1 cell adhesion molecule (L1CAM) is aberrantly expressed in malignant tumors and plays important roles in tumor progression. Thus, L1CAM could serve as a therapeutic target and anti-L1CAM antibodies may have potential as anticancer agents. However, L1CAM is expressed in neural cells and the druggab...

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Detalles Bibliográficos
Autores principales:	Cho, Seulki, Park, Insoo, Kim, Haejung, Jeong, Mun Sik, Lim, Mooney, Lee, Eung Suk, Kim, Jin Hong, Kim, Semi, Hong, Hyo Jeong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037990/ https://www.ncbi.nlm.nih.gov/pubmed/26785809 http://dx.doi.org/10.1080/19420862.2015.1125067

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