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Efficacy Projection of Obiltoxaximab for Treatment of Inhalational Anthrax across a Range of Disease Severity
Inhalational anthrax has high mortality even with antibiotic treatment, and antitoxins are now recommended as an adjunct to standard antimicrobial regimens. The efficacy of obiltoxaximab, a monoclonal antibody against anthrax protective antigen (PA), was examined in multiple studies conducted in two...
Autores principales: | Yamamoto, Brent J., Shadiack, Annette M., Carpenter, Sarah, Sanford, Daniel, Henning, Lisa N., O'Connor, Edward, Gonzales, Nestor, Mondick, John, French, Jonathan, Stark, Gregory V., Fisher, Alan C., Casey, Leslie S., Serbina, Natalya V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038317/ https://www.ncbi.nlm.nih.gov/pubmed/27431222 http://dx.doi.org/10.1128/AAC.00972-16 |
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