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Population Pharmacokinetic Modeling of Tribendimidine Metabolites in Opisthorchis viverrini-Infected Adults

There is a pressing need for alternative treatments against the liver fluke Opisthorchis viverrini. Oral tribendimidine is a promising candidate, but its population pharmacokinetic properties are unknown. Two phase IIa trials were conducted in Laos in O. viverrini-infected adults receiving single or...

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Detalles Bibliográficos
Autores principales:	Vanobberghen, Fiona, Penny, Melissa A., Duthaler, Urs, Odermatt, Peter, Sayasone, Somphou, Keiser, Jennifer, Tarning, Joel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038332/ https://www.ncbi.nlm.nih.gov/pubmed/27431233 http://dx.doi.org/10.1128/AAC.00655-16

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