Cargando…

Combined use of free light chain and heavy/light chain ratios allow diagnosis and monitoring of patients with monoclonal gammopathies: Experience of a single institute, with three exemplar case reports

Monoclonal gammopathies are characterized by serum monoclonal component (MC) plus an intact immunoglobulin and a free light chain (FLC), or a combination of both. The measurement of FLC with Freelite(®) is the standard practice recommended by International Myeloma Working Group guidelines. Recently,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gagliardi, Alfredo, Carbone, Claudio, Russo, Angela, Cuccurullo, Rosanna, Lucania, Anna, Cioppa, Paola Della, Misso, Gabriella, Caraglia, Michele, Tommasino, Catello, Mastrullo, Lucia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038391/ https://www.ncbi.nlm.nih.gov/pubmed/27698801 http://dx.doi.org/10.3892/ol.2016.4965

Ejemplares similares

Serum free light chain assays not total light chain assays are the standard of care to assess Monoclonal Gammopathies
por: Tietsche de Moraes Hungria, Vania, et al.
Publicado: (2016)

Crystal‐storing histiocytosis associated with monoclonal kappa light chain gammopathy
por: Lesesve, Jean‐François, et al.
Publicado: (2022)

Serum Free Light Chains in Neoplastic Monoclonal Gammopathies: Relative Under-Detection of Lambda Dominant Kappa/Lambda Ratio, and Underproduction of Free Lambda Light Chains, as Compared to Kappa Light Chains, in Patients With Neoplastic Monoclonal Gammopathies
por: Lee, Won Sok, et al.
Publicado: (2018)

Helicobacter pylori Infection and Light Chain Gammopathy
por: Girón, José A., et al.
Publicado: (2013)

Polyclonal serum free light chain elevation is associated with increased risk of monoclonal gammopathies
por: Kumar, Shaji, et al.
Publicado: (2019)

Clinical Comparisons of Two Free Light Chain Assays to Immunofixation Electrophoresis for Detecting Monoclonal Gammopathy
por: Kim, Han-Sung, et al.
Publicado: (2014)

Lambda light chain-induced monoclonal gammopathy of renal significance, manifesting with Fanconi Syndrome and osteomalacia
por: Gutiérrez-Peredo, Gabriel Brayan, et al.
Publicado: (2022)

P900: INVOLVED/UNINVOLVED SERUM FREE LIGHT CHAIN RATIO IS A STRONGER PREDICTOR OF DIAGNOSTIC/RISK FACTORS IN LIGHT CHAIN COMPARED TO HEAVY CHAIN MONOCLONAL GAMMOPATHIES
por: Thorir Oskarsson, Jon, et al.
Publicado: (2023)

The Value of Serum Immunoglobulin Free Light Chain Assessment in Patients with Monoclonal Gammopathies and Acute Renal Failure
por: Cirit, Mustafa, et al.
Publicado: (2012)

Comment on “Clinical Comparisons of Two Free Light Chain Assays to Immunofixation Electrophoresis for Detecting Monoclonal Gammopathy”
por: Parker, Antony R., et al.
Publicado: (2015)

Laboratory and Clinical Settings of Heavy/Light Chain (HLC) Assays in the Management of Monoclonal Gammopathies and Multiple Myeloma
por: Napodano, Cecilia, et al.
Publicado: (2023)

Monoclonal light chain crystalline podocytopathy and tubulopathy associated with monoclonal gammopathy of renal significance: a case report and literature review
por: Yu, Xiao-juan, et al.
Publicado: (2018)

Relationship between circulating syndecan-1 levels (CD138s) and serum free light chains in monoclonal gammopathies
por: Cigliana, Giovanni, et al.
Publicado: (2015)

Comparative evaluation of involved free light chain and monoclonal spike as markers for progression from monoclonal gammopathy of undetermined significance to multiple myeloma
por: Gran, Charlotte, et al.
Publicado: (2020)

Light chain–positive rod‐like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance
por: Okawara, Sayoko, et al.
Publicado: (2020)

Gamma-heavy chain monoclonal gammopathy with undetermined significance (MGUS)
por: Zushi, Yuriko, et al.
Publicado: (2019)

Acquired Fanconi syndrome secondary to light chain deposition disease associated with monoclonal gammopathy of renal significance: A case report
por: Tu, Haiyan, et al.
Publicado: (2018)

Validation Study on the Utility of Immunoglobulin Heavy/Light Chain Immunofluorescence in Kidney Biopsies With Potential Monoclonal Gammopathy of Renal Significance Lesions
por: Kudose, Satoru, et al.
Publicado: (2022)

Incidentally Detected Amyloid Light-Chain Amyloidosis Caused by Monoclonal Gammopathy of Undetermined Significance: Possible Time-Dependent Change in Colonic Findings
por: Fukui, Toshiro, et al.
Publicado: (2018)

Diffuse Peritoneal and Bowel Wall Infiltration by Light Chain-AL Amyloidosis with Omental Calcification Mimicking Abdominal Carcinomatosis – An Elderly Female with Incidental Finding of Light Chain Monoclonal Gammopathy of Undetermined Significance (LC-MGUS)
por: Junejo, Shoaib, et al.
Publicado: (2017)

IgM monoclonal gammopathy with heavy-and-light-chain amyloidosis resembling fibrillary glomerulonephritis determined by tandem mass spectrometry: a case report
por: Adachi, Misa, et al.
Publicado: (2020)

Monoclonal immunoglobulin light chains in urine of patients with lymphoma.
por: Pierson, J., et al.
Publicado: (1980)

A novel mass spectrometry method to identify the serum monoclonal light chain component in systemic light chain amyloidosis
por: Sharpley, Faye A., et al.
Publicado: (2019)

Multiple myeloma: Detection of free monoclonal light chains by modified immunofixation electrophoresis with antisera against free light chains
por: Wilhite, Dorian, et al.
Publicado: (2021)

Serum Free Light Chain Assay and κ/λ Ratio: Performance in Patients With Monoclonal Gammopathy-High False Negative Rate for κ/λ Ratio
por: Singh, Gurmukh
Publicado: (2017)

Monoclonal Gammopathy of Renal Significance with Deposits of Infrequent Morphology: Two Case Reports of Light and Heavy Chain Deposition Disease with Atypical Presentation and Literature Review
por: De La Flor, José C., et al.
Publicado: (2023)

Monoclonal gammopathies
por: Tozzi, S
Publicado: (2010)

Mapping two functional domains of clathrin light chains with monoclonal antibodies
Publicado: (1987)

Lymphoplasmacytic Lymphoma with Only Lambda Light Chain Monoclonal Paraprotein Expression
por: Cautha, Sandhya, et al.
Publicado: (2022)

Monoclonal Light Chains with alpha 2 mobility on Serum Protein Electrophoresis
por: Danalakshmi, S.
Publicado: (2023)

The evaluation and management of monoclonal gammopathy of renal significance and monoclonal gammopathy of neurological significance
por: Castillo, Jorge J., et al.
Publicado: (2021)

Light Chain Amyloidosis
por: Milani, Paolo, et al.
Publicado: (2018)

Activation of the alternative pathway of complement by monoclonal lambda light chains in membranoproliferative glomerulonephritis
Publicado: (1992)

Light Chain Restriction in Proximal Tubules—Implications for Light Chain Proximal Tubulopathy
por: Büttner-Herold, Maike, et al.
Publicado: (2022)

Light chain modulates heavy chain conformation to change protection profile of monoclonal antibodies against influenza A viruses
por: Xiao, Haixia, et al.
Publicado: (2019)

Clathrin Light Chains: Not to Be Taken so Lightly
por: Das, Jyoti, et al.
Publicado: (2021)

Tropomyosin-like properties of clathrin light chains allow a rapid, high-yield purification
Publicado: (1983)

Light chain myeloma and detection of free light chains in serum and urine of dogs and cats
por: Harris, Robert Adam, et al.
Publicado: (2021)

Monoclonal gammopathy of “ocular” significance
por: Karakus, Sezen, et al.
Publicado: (2019)

Cutaneous manifestations of monoclonal gammopathy
por: Claveau, Jean-Sebastien, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_esgoidjtcit6dvh3ivl9fpj402