Cargando…
Osthole decreases renal ischemia-reperfusion injury by suppressing JAK2/STAT3 signaling activation
Renal ischemia-reperfusion (I/R) injury is a major cause of acute kidney injury. The pathogenetic mechanisms underlying renal I/R injury involve inflammation, oxidative stress and apoptosis. Osthole is a coumarin derivative that exhibits potential anti-inflammatory activity. The aim of the present s...
Autores principales: | Luo, Lin-Na, Xie, De Qiong, Zhang, Xiao Gang, Jiang, Rong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038472/ https://www.ncbi.nlm.nih.gov/pubmed/27698686 http://dx.doi.org/10.3892/etm.2016.3603 |
Ejemplares similares
-
Protective effect of osthole on testicular ischemia/reperfusion injury in rats
por: Kocaman, Osman Hakan, et al.
Publicado: (2022) -
Dexmedetomidine protects against renal ischemia and reperfusion injury by inhibiting the JAK/STAT signaling activation
por: Si, Yanna, et al.
Publicado: (2013) -
Osthole Blocks HMGB1 Release From the Nucleus and Confers Protective Effects Against Renal Ischemia-Reperfusion Injury
por: Dai, Qing, et al.
Publicado: (2021) -
Inhibition of cerebral ischemia/reperfusion injury-induced apoptosis: nicotiflorin and JAK2/STAT3 pathway
por: Hu, Guang-qiang, et al.
Publicado: (2017) -
Edaravone alleviates cell apoptosis and mitochondrial injury in ischemia–reperfusion-induced kidney injury via the JAK/STAT pathway
por: Zhao, Xiaoying, et al.
Publicado: (2020)