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Huntington's disease: Molecular basis of pathology and status of current therapeutic approaches

Huntington's disease (HD) is a frequent and incurable hereditary neurodegenerative disorder that impairs motor and cognitive functions. Mutations in huntingtin (HTT) protein, which is essential for neuronal development, lead to the development of HD. An increase in the number of CAG repeats wit...

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Detalles Bibliográficos
Autores principales:	Huang, Wen-Juan, Chen, Wei-Wei, Zhang, Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038571/ https://www.ncbi.nlm.nih.gov/pubmed/27698679 http://dx.doi.org/10.3892/etm.2016.3566

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