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Decreased sirtuin 4 expression is associated with poor prognosis in patients with invasive breast cancer

Aberrant metabolism is a hallmark of human cancer. Glutamine metabolism has been identified as a central metabolic pathway in cancer and thus, targeting glutamine metabolism may exhibit therapeutic potential. Sirtuin 4 (SIRT4) is an important molecule that mediates the blockade of glutamine cataboli...

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Detalles Bibliográficos
Autores principales: Shi, Qingyu, Liu, Tong, Zhang, Xianyu, Geng, Jingshu, He, Xiaohui, Nu, Ming, Pang, Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038587/
https://www.ncbi.nlm.nih.gov/pubmed/27698834
http://dx.doi.org/10.3892/ol.2016.5021