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Efficacy of a Cell-Cycle Decoying Killer Adenovirus on 3-D Gelfoam(®)-Histoculture and Tumor-Sphere Models of Chemo-Resistant Stomach Carcinomatosis Visualized by FUCCI Imaging
Stomach cancer carcinomatosis peritonitis (SCCP) is a recalcitrant disease. The goal of the present study was to establish an in vitro-in vivo-like imageable model of SCCP to develop cell-cycle-based therapeutics of SCCP. We established 3-D Gelfoam(®) histoculture and tumor-sphere models of SCCP. FU...
Autores principales: | Yano, Shuya, Takehara, Kiyoto, Tazawa, Hiroshi, Kishimoto, Hiroyuki, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi, Hoffman, Robert M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038935/ https://www.ncbi.nlm.nih.gov/pubmed/27673332 http://dx.doi.org/10.1371/journal.pone.0162991 |
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