Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery

Demyelination in MS disrupts nerve signals and contributes to axon degeneration. While remyelination promises to restore lost function, it remains unclear whether remyelination will prevent axonal loss. Inflammatory demyelination is accompanied by significant neuronal loss in the experimental autoim...

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Detalles Bibliográficos
Autores principales: Mei, Feng, Lehmann-Horn, Klaus, Shen, Yun-An A, Rankin, Kelsey A, Stebbins, Karin J, Lorrain, Daniel S, Pekarek, Kara, A Sagan, Sharon, Xiao, Lan, Teuscher, Cory, von Büdingen, H-Christian, Wess, Jürgen, Lawrence, J Josh, Green, Ari J, Fancy, Stephen PJ, Zamvil, Scott S, Chan, Jonah R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039026/
https://www.ncbi.nlm.nih.gov/pubmed/27671734
http://dx.doi.org/10.7554/eLife.18246

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