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Combining Chemometric Models with Adsorption Isotherm Measurements to Study Omeprazole in RP-LC

The adsorption of the proton-pump inhibitor omeprazole was investigated using RP-LC with chemometric models combined with adsorption isotherm modelling to study the effect of pH and type of organic modifier (i.e., acetonitrile or methanol). The chemometric approach revealed that omeprazole was taili...

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Detalles Bibliográficos
Autores principales: Åsberg, Dennis, Leśko, Marek, Samuelsson, Jörgen, Karlsson, Anders, Kaczmarski, Krzysztof, Fornstedt, Torgny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039227/
https://www.ncbi.nlm.nih.gov/pubmed/27738352
http://dx.doi.org/10.1007/s10337-016-3151-8

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