Cargando…
P-Selectin Targeted Dexamethasone-Loaded Lipid Nanoemulsions: A Novel Therapy to Reduce Vascular Inflammation
Inflammation is a common process associated with numerous vascular pathologies. We hypothesized that targeting the inflamed endothelium by coupling a peptide with high affinity for P-selectin to the surface of dexamethasone-loaded lipid nanoemulsions will highly increase their specific binding to ac...
Autores principales: | Simion, Viorel, Constantinescu, Cristina Ana, Stan, Daniela, Deleanu, Mariana, Tucureanu, Monica Madalina, Butoi, Elena, Manduteanu, Ileana, Simionescu, Maya, Calin, Manuela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039295/ https://www.ncbi.nlm.nih.gov/pubmed/27703301 http://dx.doi.org/10.1155/2016/1625149 |
Ejemplares similares
-
Targeted Transfection Using PEGylated Cationic Liposomes Directed Towards P-Selectin Increases siRNA Delivery into Activated Endothelial Cells
por: Constantinescu, Cristina Ana, et al.
Publicado: (2019) -
Lipopolysaccharide-induced inflammation in monocytes/macrophages is blocked by liposomal delivery of G(i)-protein inhibitor
por: Tucureanu, Monica Madalina, et al.
Publicado: (2017) -
Functional Role of VCAM-1 Targeted Flavonoid-Loaded Lipid Nanoemulsions in Reducing Endothelium Inflammation
por: Fuior, Elena Valeria, et al.
Publicado: (2019) -
Evaluation of VCAM-1 Targeted Naringenin/Indocyanine Green-Loaded Lipid Nanoemulsions as Theranostic Nanoplatforms in Inflammation
por: Fuior, Elena Valeria, et al.
Publicado: (2020) -
The expression of MMP‐1 and MMP‐9 is up‐regulated by smooth muscle cells after their cross‐talk with macrophages in high glucose conditions
por: Macarie, Razvan Daniel, et al.
Publicado: (2018)