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Specific Inhibition of DNMT3A/ISGF3γ Interaction Increases the Temozolomide Efficiency to Reduce Tumor Growth

DNA methylation is a fundamental feature of genomes and is a candidate for pharmacological manipulation that might have important therapeutic advantage. Thus, DNA methyltransferases (DNMTs) appear to be ideal targets for drug intervention. By focusing on interactions existing between DNMT3A and DNMT...

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Detalles Bibliográficos
Autores principales:	Cheray, Mathilde, Pacaud, Romain, Nadaradjane, Arulraj, Oliver, Lisa, Vallette, François M, Cartron, Pierre-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039338/ https://www.ncbi.nlm.nih.gov/pubmed/27698935 http://dx.doi.org/10.7150/thno.9150

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