Cargando…

Depression risk in patients with coronary heart disease in Germany

AIM: To determine the prevalence of depression and its risk factors among patients with coronary heart disease (CHD) treated in German primary care practices. METHODS: Longitudinal data from nationwide general practices in Germany (n = 1072) were analyzed. Individuals initially diagnosed with CHD (2...

Descripción completa

Detalles Bibliográficos
Autores principales: Konrad, Marcel, Jacob, Louis, Rapp, Michael A, Kostev, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039356/
https://www.ncbi.nlm.nih.gov/pubmed/27721937
http://dx.doi.org/10.4330/wjc.v8.i9.547
_version_ 1782456035887284224
author Konrad, Marcel
Jacob, Louis
Rapp, Michael A
Kostev, Karel
author_facet Konrad, Marcel
Jacob, Louis
Rapp, Michael A
Kostev, Karel
author_sort Konrad, Marcel
collection PubMed
description AIM: To determine the prevalence of depression and its risk factors among patients with coronary heart disease (CHD) treated in German primary care practices. METHODS: Longitudinal data from nationwide general practices in Germany (n = 1072) were analyzed. Individuals initially diagnosed with CHD (2009-2013) were identified, and 59992 patients were included and matched (1:1) to 59992 controls. The primary outcome measure was an initial diagnosis of depression within five years after the index date among patients with and without CHD. Cox proportional hazards models were used to adjust for confounders. RESULTS: Mean age was equal to 68.0 years (SD = 11.3). A total of 55.9% of patients were men. After a five-year follow-up, 21.8% of the CHD group and 14.2% of the control group were diagnosed with depression (P < 0.001). In the multivariate regression model, CHD was a strong risk factor for developing depression (HR = 1.54, 95%CI: 1.49-1.59, P < 0.001). Prior depressive episodes, dementia, and eight other chronic conditions were associated with a higher risk of developing depression. Interestingly, older patients and women were also more likely to be diagnosed with depression compared with younger patients and men, respectively. CONCLUSION: The risk of depression is significantly increased among patients with CHD compared with patients without CHD treated in primary care practices in Germany. CHD patients should be routinely screened for depression to ensure improved treatment and management.
format Online
Article
Text
id pubmed-5039356
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Baishideng Publishing Group Inc
record_format MEDLINE/PubMed
spelling pubmed-50393562016-10-09 Depression risk in patients with coronary heart disease in Germany Konrad, Marcel Jacob, Louis Rapp, Michael A Kostev, Karel World J Cardiol Retrospective Study AIM: To determine the prevalence of depression and its risk factors among patients with coronary heart disease (CHD) treated in German primary care practices. METHODS: Longitudinal data from nationwide general practices in Germany (n = 1072) were analyzed. Individuals initially diagnosed with CHD (2009-2013) were identified, and 59992 patients were included and matched (1:1) to 59992 controls. The primary outcome measure was an initial diagnosis of depression within five years after the index date among patients with and without CHD. Cox proportional hazards models were used to adjust for confounders. RESULTS: Mean age was equal to 68.0 years (SD = 11.3). A total of 55.9% of patients were men. After a five-year follow-up, 21.8% of the CHD group and 14.2% of the control group were diagnosed with depression (P < 0.001). In the multivariate regression model, CHD was a strong risk factor for developing depression (HR = 1.54, 95%CI: 1.49-1.59, P < 0.001). Prior depressive episodes, dementia, and eight other chronic conditions were associated with a higher risk of developing depression. Interestingly, older patients and women were also more likely to be diagnosed with depression compared with younger patients and men, respectively. CONCLUSION: The risk of depression is significantly increased among patients with CHD compared with patients without CHD treated in primary care practices in Germany. CHD patients should be routinely screened for depression to ensure improved treatment and management. Baishideng Publishing Group Inc 2016-09-26 2016-09-26 /pmc/articles/PMC5039356/ /pubmed/27721937 http://dx.doi.org/10.4330/wjc.v8.i9.547 Text en ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Retrospective Study
Konrad, Marcel
Jacob, Louis
Rapp, Michael A
Kostev, Karel
Depression risk in patients with coronary heart disease in Germany
title Depression risk in patients with coronary heart disease in Germany
title_full Depression risk in patients with coronary heart disease in Germany
title_fullStr Depression risk in patients with coronary heart disease in Germany
title_full_unstemmed Depression risk in patients with coronary heart disease in Germany
title_short Depression risk in patients with coronary heart disease in Germany
title_sort depression risk in patients with coronary heart disease in germany
topic Retrospective Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039356/
https://www.ncbi.nlm.nih.gov/pubmed/27721937
http://dx.doi.org/10.4330/wjc.v8.i9.547
work_keys_str_mv AT konradmarcel depressionriskinpatientswithcoronaryheartdiseaseingermany
AT jacoblouis depressionriskinpatientswithcoronaryheartdiseaseingermany
AT rappmichaela depressionriskinpatientswithcoronaryheartdiseaseingermany
AT kostevkarel depressionriskinpatientswithcoronaryheartdiseaseingermany