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Diet- and Genetically-induced Obesity Produces Alterations in the Microbiome, Inflammation and Wnt Pathway in the Intestine of Apc(+/1638N) Mice: Comparisons and Contrasts
Obesity is an established risk factor for colorectal cancer (CRC). Our previous study indicated that obesity increases activity of the pro-tumorigenic Wnt-signaling. Presently, we sought to further advance our understanding of the mechanisms by which obesity promotes CRC by examining associations be...
Autores principales: | Liu, Wei, Crott, Jimmy W., Lyu, Lin, Pfalzer, Anna C., Li, Jinchao, Choi, Sang-Woon, Yang, Yingke, Mason, Joel B., Liu, Zhenhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039360/ https://www.ncbi.nlm.nih.gov/pubmed/27698916 http://dx.doi.org/10.7150/jca.15792 |
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