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Detecting Circulating Tumor DNA in Hepatocellular Carcinoma Patients Using Droplet Digital PCR Is Feasible and Reflects Intratumoral Heterogeneity
Purpose: Circulating tumor DNA (ctDNA) is increasingly recognized as liquid biopsy to profile tumor genome. Droplet digital PCR (ddPCR) is a highly sensitive and easily operable platform for mutant detection. Here, we tried to detect ctDNA in hepatocellular carcinoma (HCC) patients using ddPCR. Meth...
Autores principales: | Huang, Ao, Zhang, Xin, Zhou, Shao-Lai, Cao, Ya, Huang, Xiao-Wu, Fan, Jia, Yang, Xin-Rong, Zhou, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039376/ https://www.ncbi.nlm.nih.gov/pubmed/27698932 http://dx.doi.org/10.7150/jca.15823 |
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