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Prediction of new drug indications based on clinical data and network modularity
Drug repositioning is commonly done within the drug discovery process in order to adjust or expand the application line of an active molecule. Previous computational methods in this domain mainly focused on shared genes or correlations between genes to construct new drug-disease associations. We pro...
Autores principales: | Yu, Liang, Ma, Xiaoke, Zhang, Long, Zhang, Jing, Gao, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039412/ https://www.ncbi.nlm.nih.gov/pubmed/27678071 http://dx.doi.org/10.1038/srep32530 |
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