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Postnatal onset of retinal degeneration by loss of embryonic Ezh2 repression of Six1

Some adult-onset disorders may be linked to dysregulated embryonic development, yet the mechanisms underlying this association remain poorly understood. Congenital retinal degenerative diseases are blinding disorders characterized by postnatal degeneration of photoreceptors, and affect nearly 2 mill...

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Detalles Bibliográficos
Autores principales: Yan, Naihong, Cheng, Lin, Cho, Kinsang, Malik, Muhammad Taimur A., Xiao, Lirong, Guo, Chenying, Yu, Honghua, Zhu, Ruilin, Rao, Rajesh C., Chen, Dong Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039414/
https://www.ncbi.nlm.nih.gov/pubmed/27677711
http://dx.doi.org/10.1038/srep33887