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Inhibition of Bacterial RNase P RNA by Phenothiazine Derivatives

There is a need to identify novel scaffolds and targets to develop new antibiotics. Methylene blue is a phenothiazine derivative, and it has been shown to possess anti-malarial and anti-trypanosomal activities. Here, we show that different phenothiazine derivatives and pyronine G inhibited the activ...

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Detalles Bibliográficos
Autores principales: Wu, Shiying, Mao, Guanzhong, Kirsebom, Leif A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039424/
https://www.ncbi.nlm.nih.gov/pubmed/27618117
http://dx.doi.org/10.3390/biom6030038

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