Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells

Background: Hierridin B was isolated from a marine cyanobacterium Cyanobium sp. strain and induced cytotoxicity selectively in HT-29 adenocarcinoma cells. The underlying molecular mechanism was not yet elucidated. Methods: HT-29 cells were exposed to the IC(50) concentration of hierridin B (100.2 μM...

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Detalles Bibliográficos
Autores principales: Freitas, Sara, Martins, Rosário, Costa, Margarida, Leão, Pedro N., Vitorino, Rui, Vasconcelos, Vitor, Urbatzka, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039529/
https://www.ncbi.nlm.nih.gov/pubmed/27589771
http://dx.doi.org/10.3390/md14090158

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