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Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels
Voltage-sensor domains (VSDs) are modular transmembrane domains of voltage-gated ion channels that respond to changes in membrane potential by undergoing conformational changes that are coupled to gating of the ion-conducting pore. Most spider-venom peptides function as gating modifiers by binding t...
Autores principales: | Lau, Carus H. Y., King, Glenn F., Mobli, Mehdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039624/ https://www.ncbi.nlm.nih.gov/pubmed/27677715 http://dx.doi.org/10.1038/srep34333 |
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