A new design for a green calcium indicator with a smaller size and a reduced number of calcium-binding sites

Genetically encoded calcium indicators (GECIs) are mainly represented by two- or one-fluorophore-based sensors. One type of two-fluorophore-based sensor, carrying Opsanus troponin C (TnC) as the Ca(2+)-binding moiety, has two binding sites for calcium ions, providing a linear response to calcium ion...

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Detalles Bibliográficos
Autores principales: Barykina, Natalia V., Subach, Oksana M., Doronin, Danila A., Sotskov, Vladimir P., Roshchina, Marina A., Kunitsyna, Tatiana A., Malyshev, Aleksey Y., Smirnov, Ivan V., Azieva, Asya M., Sokolov, Ilya S., Piatkevich, Kiryl D., Burtsev, Mikhail S., Varizhuk, Anna M., Pozmogova, Galina E., Anokhin, Konstantin V., Subach, Fedor V., Enikolopov, Grigori N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039633/
https://www.ncbi.nlm.nih.gov/pubmed/27677952
http://dx.doi.org/10.1038/srep34447

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