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Bioluminescence Microscopy as a Method to Measure Single Cell Androgen Receptor Activity Heterogeneous Responses to Antiandrogens

Cancer cell heterogeneity is well-documented. Therefore, techniques to monitor single cell heterogeneous responses to treatment are needed. We developed a highly translational and quantitative bioluminescence microscopy method to measure single cell androgen receptor (AR) activity modulation by anti...

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Detalles Bibliográficos
Autores principales: Jain, Pallavi, Neveu, Bertrand, Velot, Lauriane, Wu, Lily, Fradet, Yves, Pouliot, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039635/
https://www.ncbi.nlm.nih.gov/pubmed/27678181
http://dx.doi.org/10.1038/srep33968