Cargando…
Conditional abrogation of Atm in osteoclasts extends osteoclast lifespan and results in reduced bone mass
Ataxia-telangiectasia mutated (ATM) kinase is a central component involved in the signal transduction of the DNA damage response (DDR) and thus plays a critical role in the maintenance of genomic integrity. Although the primary functions of ATM are associated with the DDR, emerging data suggest that...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039636/ https://www.ncbi.nlm.nih.gov/pubmed/27677594 http://dx.doi.org/10.1038/srep34426 |