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Activation of GLP-1 Receptor Enhances Neuronal Base Excision Repair via PI3K-AKT-Induced Expression of Apurinic/Apyrimidinic Endonuclease 1

Glucagon-like peptide-1 (GLP-1) is an intestinal-secreted incretin that increases cellular glucose up-take to decrease blood sugar. Recent studies, however, suggest that the function of GLP-1 is not only to decrease blood sugar, but also acts as a neurotrophic factor that plays a role in neuronal su...

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Detalles Bibliográficos
Autores principales: Yang, Jenq-Lin, Chen, Wei-Yu, Chen, Yin-Ping, Kuo, Chao-Ying, Chen, Shang-Der
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039677/
https://www.ncbi.nlm.nih.gov/pubmed/27698937
http://dx.doi.org/10.7150/thno.15993

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