Cargando…
Blocking the 4-1BB Pathway Ameliorates Crystalline Silica-induced Lung Inflammation and Fibrosis in Mice
Long term pulmonary exposure to crystalline silica leads to silicosis that manifests progressive interstitial fibrosis, eventually leading to respiratory failure and death. Despite efforts to eliminate silicosis, clinical cases continue to occur in both developing and developed countries. The exact...
Autores principales: | Li, Chao, Du, Sitong, Lu, Yiping, Lu, Xiaowei, Liu, Fangwei, Chen, Ying, Weng, Dong, Chen, Jie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039680/ https://www.ncbi.nlm.nih.gov/pubmed/27698940 http://dx.doi.org/10.7150/thno.16180 |
Ejemplares similares
-
4-1BB Signaling Promotes Alveolar Macrophages-Mediated Pro-Fibrotic Responses and Crystalline Silica-Induced Pulmonary Fibrosis in Mice
por: Lu, Yiping, et al.
Publicado: (2018) -
Dioscin Exerts Protective Effects Against Crystalline Silica-induced Pulmonary Fibrosis in Mice
por: Li, Chao, et al.
Publicado: (2017) -
Dioscin Alleviates Crystalline Silica-Induced Pulmonary Inflammation and Fibrosis through Promoting Alveolar Macrophage Autophagy
por: Du, Sitong, et al.
Publicado: (2019) -
Blockade of Wnt/β-Catenin Pathway Aggravated Silica-Induced Lung Inflammation through Tregs Regulation on Th Immune Responses
por: Dai, Wujing, et al.
Publicado: (2016) -
IL-10-Producing B Cells Suppress Effector T Cells Activation and Promote Regulatory T Cells in Crystalline Silica-Induced Inflammatory Response In Vitro
por: Lu, Yiping, et al.
Publicado: (2017)