Cargando…
In Utero Caffeine Exposure Induces Transgenerational Effects on the Adult Heart
Each year millions of pregnant woman are exposed to caffeine, which acts to antagonize adenosine action. The long-term consequences of this exposure on the developing fetus are largely unknown, although in animal models we have found adverse effects on cardiac function. To assess if these effects ar...
Autores principales: | Fang, Xiefan, Poulsen, Ryan R., Rivkees, Scott A., Wendler, Christopher C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039698/ https://www.ncbi.nlm.nih.gov/pubmed/27677355 http://dx.doi.org/10.1038/srep34106 |
Ejemplares similares
-
Embryonic Caffeine Exposure Acts via A1 Adenosine Receptors to Alter Adult Cardiac Function and DNA Methylation in Mice
por: Buscariollo, Daniela L., et al.
Publicado: (2014) -
Knockdown of DNA methyltransferase 1 reduces DNA methylation and alters expression patterns of cardiac genes in embryonic cardiomyocytes
por: Fang, Xiefan, et al.
Publicado: (2021) -
Caffeine Acts via A1 Adenosine Receptors to Disrupt Embryonic Cardiac Function
por: Buscariollo, Daniela L., et al.
Publicado: (2011) -
Identification of the heart as the critical site of adenosine mediated embryo protection
por: Wendler, Christopher C, et al.
Publicado: (2010) -
The Sphingosine-1-phospate receptor 1 mediates S1P action during cardiac development
por: Poulsen, Ryan R, et al.
Publicado: (2011)