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RNA-seq analysis of the hypothalamic transcriptome reveals the networks regulating physiopathological progress in the diabetic GK rat

The Goto-Kakizaki (GK) rat is an animal model of non-obese type 2 diabetes (T2D). The GK rat was generated through the introduction of various genetic mutations from continuous inbreeding; these rats develop diabetes spontaneously. The mutated genes in GK rats may play key roles in the regulation of...

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Detalles Bibliográficos
Autores principales: Meng, Yuhuan, Guan, Yujia, Zhang, Wenlu, Wu, Yu-e, Jia, Huanhuan, Zhang, Yu, Zhang, Xiuqing, Du, Hongli, Wang, Xiaoning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039700/
https://www.ncbi.nlm.nih.gov/pubmed/27677945
http://dx.doi.org/10.1038/srep34138