Cargando…
Evidence for Direct Control of Virulence and Defense Gene Circuits by the Pseudomonas aeruginosa Quorum Sensing Regulator, MvfR
Pseudomonas aeruginosa defies eradication by antibiotics and is responsible for acute and chronic human infections due to a wide variety of virulence factors. Currently, it is believed that MvfR (PqsR) controls the expression of many of these factors indirectly via the pqs and phnAB operons. Here we...
Autores principales: | Maura, Damien, Hazan, Ronen, Kitao, Tomoe, Ballok, Alicia E., Rahme, Laurence G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039717/ https://www.ncbi.nlm.nih.gov/pubmed/27678057 http://dx.doi.org/10.1038/srep34083 |
Ejemplares similares
-
In-depth Profiling of MvfR-Regulated Small Molecules in Pseudomonas aeruginosa after Quorum Sensing Inhibitor Treatment
por: Allegretta, Giuseppe, et al.
Publicado: (2017) -
MvfR Controls Tolerance to Polymyxin B by Regulating rfaD in Pseudomonas aeruginosa
por: Yang, Fan, et al.
Publicado: (2023) -
Structural Basis for Native Agonist and Synthetic Inhibitor Recognition by the Pseudomonas aeruginosa Quorum Sensing Regulator PqsR (MvfR)
por: Ilangovan, Aravindan, et al.
Publicado: (2013) -
Molecular Insights into Binding Mode and Interactions of Structure-Based Virtually Screened Inhibitors for Pseudomonas aeruginosa Multiple Virulence Factor Regulator (MvfR)
por: Almihyawi, Raed A. H., et al.
Publicado: (2021) -
Drug Repurposing Targeting Pseudomonas aeruginosa MvfR Using Docking, Virtual Screening, Molecular Dynamics, and Free-Energy Calculations
por: Vieira, Tatiana F., et al.
Publicado: (2022)