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Getting to S: CDK functions and targets on the path to cell-cycle commitment

How and when eukaryotic cells make the irrevocable commitment to divide remain central questions in the cell-cycle field. Parallel studies in yeast and mammalian cells seemed to suggest analogous control mechanisms operating during the G1 phase—at Start or the restriction (R) point, respectively—to...

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Detalles Bibliográficos
Autor principal: Fisher, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040153/
https://www.ncbi.nlm.nih.gov/pubmed/27746911
http://dx.doi.org/10.12688/f1000research.9463.1