Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses

PURPOSE: Recent studies indicate that mitochondrial proteins may contribute to the pathogenesis of primary open-angle glaucoma (POAG). In this study, we examined the association between POAG and common variations in gene-encoding mitochondrial proteins. METHODS: We examined genetic data from 3430 PO...

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Detalles Bibliográficos
Autores principales: Khawaja, Anthony P., Cooke Bailey, Jessica N., Kang, Jae Hee, Allingham, R. Rand, Hauser, Michael A., Brilliant, Murray, Budenz, Donald L., Christen, William G., Fingert, John, Gaasterland, Douglas, Gaasterland, Terry, Kraft, Peter, Lee, Richard K., Lichter, Paul R., Liu, Yutao, Medeiros, Felipe, Moroi, Syoko E., Richards, Julia E., Realini, Tony, Ritch, Robert, Schuman, Joel S., Scott, William K., Singh, Kuldev, Sit, Arthur J., Vollrath, Douglas, Wollstein, Gadi, Zack, Donald J., Zhang, Kang, Pericak-Vance, Margaret, Weinreb, Robert N., Haines, Jonathan L., Pasquale, Louis R., Wiggs, Janey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040191/
https://www.ncbi.nlm.nih.gov/pubmed/27661856
http://dx.doi.org/10.1167/iovs.16-20017

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