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Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma
PURPOSE: The purpose of this analysis was to assess the utility of Pitx2(+/−) mice as a model for the ocular features of Axenfeld-Rieger Syndrome and for congenital glaucoma. METHODS: Eyes of Pitx2(+/−) and wild-type littermates were examined clinically using optical coherence tomography (OCT) and f...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040192/ https://www.ncbi.nlm.nih.gov/pubmed/27654429 http://dx.doi.org/10.1167/iovs.16-19700 |