Cargando…
DC-159a Shows Inhibitory Activity against DNA Gyrases of Mycobacterium leprae
BACKGROUND: Fluoroquinolones are a class of antibacterial agents used for leprosy treatment. Some new fluoroquinolones have been attracting interest due to their remarkable potency that is reportedly better than that of ofloxacin, the fluoroquinolone currently recommended for treatment of leprosy. F...
Autores principales: | Yamaguchi, Tomoyuki, Yokoyama, Kazumasa, Nakajima, Chie, Suzuki, Yasuhiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040261/ https://www.ncbi.nlm.nih.gov/pubmed/27681932 http://dx.doi.org/10.1371/journal.pntd.0005013 |
Ejemplares similares
-
Impact of Amino Acid Substitutions in B Subunit of DNA Gyrase in Mycobacterium leprae on Fluoroquinolone Resistance
por: Yokoyama, Kazumasa, et al.
Publicado: (2012) -
DNA gyrase could be a crucial regulatory factor for growth and survival of Mycobacterium leprae
por: Kim, Hyun, et al.
Publicado: (2019) -
Characterization of DNA Gyrase Activity and Elucidation of the Impact of Amino Acid Substitution in GyrA on Fluoroquinolone Resistance in Mycobacterium avium
por: Thapa, Jeewan, et al.
Publicado: (2023) -
Molecular Characterization of Mycobacterium ulcerans DNA Gyrase and Identification of Mutations Reducing Susceptibility to Quinolones In Vitro
por: Kim, Hyun, et al.
Publicado: (2022) -
Pathogenicity and virulence of Mycobacterium leprae
por: Sugawara-Mikami, Mariko, et al.
Publicado: (2022)