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Neuropeptide Y Overexpressing Female and Male Mice Show Divergent Metabolic but Not Gut Microbial Responses to Prenatal Metformin Exposure
BACKGROUND: Prenatal metformin exposure has been shown to improve the metabolic outcome in the offspring of high fat diet fed dams. However, if this is evident also in a genetic model of obesity and whether gut microbiota has a role, is not known. METHODS: The metabolic effects of prenatal metformin...
Autores principales: | Salomäki-Myftari, Henriikka, Vähätalo, Laura H., Ailanen, Liisa, Pietilä, Sami, Laiho, Asta, Hänninen, Arno, Pursiheimo, Juha-Pekka, Munukka, Eveliina, Rintala, Anniina, Savontaus, Eriika, Pesonen, Ullamari, Koulu, Markku |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040270/ https://www.ncbi.nlm.nih.gov/pubmed/27681875 http://dx.doi.org/10.1371/journal.pone.0163805 |
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