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Using baseline cognitive severity for enriching Alzheimer's disease clinical trials: How does Mini-Mental State Examination predict rate of change?

BACKGROUND: Post hoc analyses from clinical trials in Alzheimer's disease (AD) suggest that more cognitively impaired participants respond differently from less impaired on cognitive outcomes. We examined pooled clinical trials data to assess the utility of enriching trials using baseline cogni...

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Detalles Bibliográficos
Autores principales:	Kennedy, Richard E., Cutter, Gary R., Wang, Guoqiao, Schneider, Lon S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Featured Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040516/ https://www.ncbi.nlm.nih.gov/pubmed/27695707 http://dx.doi.org/10.1016/j.trci.2015.03.001

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