Cargando…

The Arabidopsis NMD Factor UPF3 Is Feedback-Regulated at Multiple Levels and Plays a Role in Plant Response to Salt Stress

Nonsense-mediated mRNA decay (NMD) is a eukaryotic RNA surveillance mechanism that degrades aberrant transcripts and controls the levels of many normal mRNAs. It was shown that balanced expression of the NMD factor UPF3 is essential for the maintenance of proper NMD homeostasis in Arabidopsis. UPF3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vexler, Karina, Cymerman, Miryam A., Berezin, Irina, Fridman, Adi, Golani, Linoy, Lasnoy, Michal, Saul, Helen, Shaul, Orit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Plant Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040709/ https://www.ncbi.nlm.nih.gov/pubmed/27746786 http://dx.doi.org/10.3389/fpls.2016.01376

Ejemplares similares

The feedback control of UPF3 is crucial for RNA surveillance in plants
por: Degtiar, Evgeniya, et al.
Publicado: (2015)

The role of the NMD factor UPF3B in olfactory sensory neurons
por: Tan, Kun, et al.
Publicado: (2020)

Progression of the pluripotent epiblast depends upon the NMD factor UPF2
por: Chousal, Jennifer N., et al.
Publicado: (2022)

Insights into the Effects of Cancer Associated Mutations at the UPF2 and ATP-Binding Sites of NMD Master Regulator: UPF1
por: Kalathiya, Umesh, et al.
Publicado: (2019)

In Silico Analysis of the Structural and Biochemical Features of the NMD Factor UPF1 in Ustilago maydis
por: Martínez-Montiel, Nancy, et al.
Publicado: (2016)

A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD
por: Nicholson, Pamela, et al.
Publicado: (2014)

mRNAs containing NMD-competent premature termination codons are stabilized and translated under UPF1 depletion
por: Kim, Won Kyu, et al.
Publicado: (2017)

Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5–SMG7 and SMG6
por: Chakrabarti, Sutapa, et al.
Publicado: (2014)

N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD
por: Okada-Katsuhata, Yukiko, et al.
Publicado: (2012)

The RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNA
por: Geißler, Verena, et al.
Publicado: (2013)

(Phospho)proteomic Profiling of Microsatellite Unstable CRC Cells Reveals Alterations in Nuclear Signaling and Cholesterol Metabolism Caused by Frameshift Mutation of NMD Regulator UPF3A
por: Michalak, Malwina, et al.
Publicado: (2020)

The leader intron of AtMHX can elicit, in the absence of splicing, low-level intron-mediated enhancement that depends on the internal intron sequence
por: Akua, Tsofit, et al.
Publicado: (2010)

Elucidation of the Mechanism of Host NMD Suppression by HTLV-1 Rex: Dissection of Rex to Identify the NMD Inhibitory Domain
por: Nakano, Kazumi, et al.
Publicado: (2022)

A regulated NMD mouse model supports NMD inhibition as a viable therapeutic option to treat genetic diseases
por: Echols, Josh, et al.
Publicado: (2020)

Arabidopsis NMD3 Is Required for Nuclear Export of 60S Ribosomal Subunits and Affects Secondary Cell Wall Thickening
por: Chen, Mei-Qin, et al.
Publicado: (2012)

NMD monitors translational fidelity 24/7
por: Celik, Alper, et al.
Publicado: (2017)

HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA
por: Ajamian, Lara, et al.
Publicado: (2015)

Environmental stresses suppress nonsense-mediated mRNA decay (NMD) and affect cells by stabilizing NMD-targeted gene expression
por: Usuki, Fusako, et al.
Publicado: (2019)

The Arabidopsis thaliana MHX gene includes an intronic element that boosts translation when localized in a 5′ UTR intron
por: Akua, Tsofit, et al.
Publicado: (2013)

UPF1/circRPPH1/ATF3 feedback loop promotes the malignant phenotype and stemness of GSCs
por: Xu, Jinkun, et al.
Publicado: (2022)

Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies
por: Durand, Sébastien, et al.
Publicado: (2007)

A Role for Nonsense-Mediated mRNA Decay in Plants: Pathogen Responses Are Induced in Arabidopsis thaliana NMD Mutants
por: Rayson, Samantha, et al.
Publicado: (2012)

The salicylic acid dependent and independent effects of NMD in plants
por: Rayson, Samantha, et al.
Publicado: (2012)

Human NMD ensues independently of stable ribosome stalling
por: Karousis, Evangelos D., et al.
Publicado: (2020)

Gene Replacement in Arabidopsis Reveals Manganese Transport as an Ancient Feature of Human, Plant and Cyanobacterial UPF0016 Proteins
por: Hoecker, Natalie, et al.
Publicado: (2021)

Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation
por: Bufton, Joshua C, et al.
Publicado: (2022)

Human UPF3A and UPF3B enable fault‐tolerant activation of nonsense‐mediated mRNA decay
por: Wallmeroth, Damaris, et al.
Publicado: (2022)

Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe
por: Wen, Jikai, et al.
Publicado: (2010)

Large-Scale Evidence for Conservation of NMD Candidature Across Mammals
por: de Lima Morais, David A., et al.
Publicado: (2010)

Longevity regulation by NMD-mediated mRNA quality control
por: Son, Heehwa G., et al.
Publicado: (2017)

Selective destabilization of polypeptides synthesized from NMD-targeted transcripts
por: Chu, Vincent, et al.
Publicado: (2021)

The RNA surveillance proteins UPF1, UPF2 and SMG6 affect HIV-1 reactivation at a post-transcriptional level
por: Rao, Shringar, et al.
Publicado: (2018)

Interaction Between LncRNA and UPF1 in Tumors
por: He, Junjian, et al.
Publicado: (2021)

Phylogeny and a structural model of plant MHX transporters
por: Gaash, Rachel, et al.
Publicado: (2013)

Association between NMD3 and symptoms of Parkinson’s disease in Chinese patients
por: Wu, Hui, et al.
Publicado: (2020)

Recurrent SRSF2 mutations in MDS affect both splicing and NMD
por: Rahman, Mohammad Alinoor, et al.
Publicado: (2020)

Nanopore sequencing reveals endogenous NMD-targeted isoforms in human cells
por: Karousis, Evangelos D., et al.
Publicado: (2021)

The NMD Pathway Regulates GABARAPL1 mRNA during the EMT
por: Baudu, Timothée, et al.
Publicado: (2021)

Mammalian UPF3A and UPF3B can activate nonsense‐mediated mRNA decay independently of their exon junction complex binding
por: Yi, Zhongxia, et al.
Publicado: (2022)

The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma
por: Polaski, Jacob T, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_a718kptth5s3j5956fme6gs5v1