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Intestinal permeability to iohexol as an in vivo marker of chemotherapy-induced gastrointestinal toxicity in Sprague–Dawley rats

PURPOSE: Gastrointestinal toxicity is the most common adverse effect of chemotherapy. Chemotherapeutic drugs damage the intestinal mucosa and increase intestinal permeability. Intestinal permeability is one of the key markers of gastrointestinal function and measuring intestinal permeability could s...

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Detalles Bibliográficos
Autores principales: Forsgård, Richard A., Korpela, Riitta, Holma, Reetta, Lindén, Jere, Frias, Rafael, Spillmann, Thomas, Österlund, Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040744/
https://www.ncbi.nlm.nih.gov/pubmed/27590707
http://dx.doi.org/10.1007/s00280-016-3150-3