Rescue of the 1947 Zika Virus Prototype Strain with a Cytomegalovirus Promoter-Driven cDNA Clone

The recent Zika virus (ZIKV) outbreak has been linked to severe pathogenesis. Here, we report the construction of a plasmid carrying a cytomegalovirus (CMV) promoter-expressed prototype 1947 Uganda MR766 ZIKV cDNA that can initiate infection following direct plasmid DNA transfection of mammalian cel...

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Detalles Bibliográficos
Autores principales: Schwarz, Megan C., Sourisseau, Marion, Espino, Michael M., Gray, Essanna S., Chambers, Matthew T., Tortorella, Domenico, Evans, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040786/
https://www.ncbi.nlm.nih.gov/pubmed/27704051
http://dx.doi.org/10.1128/mSphere.00246-16

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