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Regulation of aPKC activity by Nup358 dependent SUMO modification

Atypical PKC (aPKC) family members are involved in regulation of diverse cellular processes, including cell polarization. aPKCs are known to be activated by phosphorylation of specific threonine residues in the activation loop and turn motif. They can also be stimulated by interaction with Cdc42~GTP...

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Detalles Bibliográficos
Autores principales: Yadav, Santosh Kumar, Magre, Indrasen, Singh, Aditi, Khuperkar, Deepak, Joseph, Jomon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040961/
https://www.ncbi.nlm.nih.gov/pubmed/27682244
http://dx.doi.org/10.1038/srep34100

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