Cargando…

Monitoring of the Immune Dysfunction in Cancer Patients

Immunotherapy shows promising clinical results in patients with different types of cancer, but its full potential is not reached due to immune dysfunction as a result of several suppressive mechanisms that play a role in cancer development and progression. Monitoring of immune dysfunction is a prere...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santegoets, Saskia J. A. M., Welters, Marij J. P., van der Burg, Sjoerd H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041023/ https://www.ncbi.nlm.nih.gov/pubmed/27598210 http://dx.doi.org/10.3390/vaccines4030029

Ejemplares similares

Detection and functional assessment of regulatory T cells in clinical samples
por: Santegoets, Saskia, et al.
Publicado: (2014)

The Tumor Microenvironment and Immunotherapy of Oropharyngeal Squamous Cell Carcinoma
por: Welters, Marij J. P., et al.
Publicado: (2020)

The combined HPV16-E2/E6/E7 T cell response in oropharyngeal cancer predicts superior survival
por: Santegoets, Saskia J., et al.
Publicado: (2023)

EGFR signaling suppresses type 1 cytokine-induced T-cell attracting chemokine secretion in head and neck cancer
por: Ma, Wenbo, et al.
Publicado: (2018)

Standard radiotherapy but not chemotherapy impairs systemic immunity in non-small cell lung cancer
por: Talebian Yazdi, Mehrdad, et al.
Publicado: (2016)

Managing Multi-center Flow Cytometry Data for Immune Monitoring
por: White, Scott, et al.
Publicado: (2015)

The common HLA class I-restricted tumor-infiltrating T cell response in HPV16-induced cancer
por: Santegoets, Saskia J., et al.
Publicado: (2022)

Low-dose interferon-alpha preconditioning and adoptive cell therapy in patients with metastatic melanoma refractory to standard (immune) therapies: a phase I/II study
por: Verdegaal, Els, et al.
Publicado: (2020)

CD163(+) cytokine-producing cDC2 stimulate intratumoral type 1 T cell responses in HPV16-induced oropharyngeal cancer
por: Santegoets, Saskia J, et al.
Publicado: (2020)

Tumor-specific T cells support chemokine-driven spatial organization of intratumoral immune microaggregates needed for long survival
por: Abdulrahman, Ziena, et al.
Publicado: (2022)

Human papillomavirus 16-specific cell-mediated immunity in children born to mothers with incident cervical intraepithelial neoplasia (CIN) and to those constantly HPV negative
por: Koskimaa, Hanna-Mari, et al.
Publicado: (2015)

Timed adoptive T cell transfer during chemotherapy in patients with recurrent platinum-sensitive epithelial ovarian cancer
por: Verdegaal, Els M E, et al.
Publicado: (2023)

Local and systemic XAGE-1b-specific immunity in patients with lung adenocarcinoma
por: Talebian Yazdi, Mehrdad, et al.
Publicado: (2015)

Cell mediated immunity against HPV16 E2, E6 and E7 peptides in women with incident CIN and in constantly HPV-negative women followed-up for 10-years
por: Paaso, Anna, et al.
Publicado: (2015)

Interferon‐γ and IL‐5 associated cell‐mediated immune responses to HPV16 E2 and E6 distinguish between persistent oral HPV16 infections and noninfected mucosa
por: Paaso, Anna, et al.
Publicado: (2021)

Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry
por: Santegoets, Saskia J. A. M., et al.
Publicado: (2015)

Predictive Biomarkers for Outcomes of Immune Checkpoint Inhibitors (ICIs) in Melanoma: A Systematic Review
por: Baltussen, Joosje C., et al.
Publicado: (2021)

Harmonization of the intracellular cytokine staining assay
por: Welters, Marij J. P., et al.
Publicado: (2012)

A phase 1/2 study combining gemcitabine, Pegintron and p53 SLP vaccine in patients with platinum-resistant ovarian cancer
por: Dijkgraaf, Eveline M., et al.
Publicado: (2015)

High numbers of activated helper T cells are associated with better clinical outcome in early stage vulvar cancer, irrespective of HPV or p53 status
por: Kortekaas, Kim E., et al.
Publicado: (2019)

Human papillomavirus 16 E2-, E6- and E7-specific T-cell responses in children and their mothers who developed incident cervical intraepithelial neoplasia during a 14-year follow-up of the Finnish Family HPV cohort
por: Koskimaa, Hanna-Mari, et al.
Publicado: (2014)

Pre-existing inflammatory immune microenvironment predicts the clinical response of vulvar high-grade squamous intraepithelial lesions to therapeutic HPV16 vaccination
por: Abdulrahman, Ziena, et al.
Publicado: (2020)

Tbet-positive regulatory T cells accumulate in oropharyngeal cancers with ongoing tumor-specific type 1 T cell responses
por: Santegoets, S. J., et al.
Publicado: (2019)

CD161 expression and regulation defines rapidly responding effector CD4+ T cells associated with improved survival in HPV16-associated tumors
por: Duurland, Chantal L, et al.
Publicado: (2022)

High-Risk Human Papillomavirus Targets Crossroads in Immune Signaling
por: Tummers, Bart, et al.
Publicado: (2015)

Human Papillary and Reticular Fibroblasts Show Distinct Functions on Tumor Behavior in 3D-Organotypic Cultures Mimicking Melanoma and HNSCC
por: Wu, Shidi, et al.
Publicado: (2022)

Hierarchical Modeling for Rare Event Detection and Cell Subset Alignment across Flow Cytometry Samples
por: Cron, Andrew, et al.
Publicado: (2013)

Photochemical Internalization Enhanced Vaccination Is Safe, and Gives Promising Cellular Immune Responses to an HPV Peptide-Based Vaccine in a Phase I Clinical Study in Healthy Volunteers
por: Otterhaug, Tone, et al.
Publicado: (2021)

Primary vulvar squamous cell carcinomas with high T cell infiltration and active immune signaling are potential candidates for neoadjuvant PD-1/PD-L1 immunotherapy
por: Kortekaas, Kim E, et al.
Publicado: (2021)

Toward harmonized phenotyping of human myeloid-derived suppressor cells by flow cytometry: results from an interim study
por: Mandruzzato, Susanna, et al.
Publicado: (2016)

The simultaneous ex vivo detection of low-frequency antigen-specific CD4+ and CD8+ T-cell responses using overlapping peptide pools
por: Singh, Satwinder Kaur, et al.
Publicado: (2012)

Serum-free freezing media support high cell quality and excellent ELISPOT assay performance across a wide variety of different assay protocols
por: Filbert, Helene, et al.
Publicado: (2012)

CD47/SIRPα axis: bridging innate and adaptive immunity
por: van Duijn, Anneloes, et al.
Publicado: (2022)

Short-Term Fasting Synergizes with Solid Cancer Therapy by Boosting Antitumor Immunity
por: de Gruil, Nadia, et al.
Publicado: (2022)

The blood mMDSC to DC ratio is a sensitive and easy to assess independent predictive factor for epithelial ovarian cancer survival
por: Santegoets, S. J. A. M., et al.
Publicado: (2018)

Identification and manipulation of tumor associated macrophages in human cancers
por: Heusinkveld, Moniek, et al.
Publicado: (2011)

NKG2A is a late immune checkpoint on CD8 T cells and marks repeated stimulation and cell division
por: Borst, Linda, et al.
Publicado: (2021)

Future Challenges in Cancer Resistance to Immunotherapy
por: van Elsas, Marit J., et al.
Publicado: (2020)

A beneficial tumor microenvironment in oropharyngeal squamous cell carcinoma is characterized by a high T cell and low IL-17(+) cell frequency
por: Punt, Simone, et al.
Publicado: (2016)

TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients
por: Zom, Gijs G., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_n543ktda8o45frgtsb9or52mho