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Inhibition of transforming growth factor β-activated kinase 1 prevents inflammation-related cartilage degradation in osteoarthritis

Osteoarthritis (OA) is a common debilitating joint disorder, there’s still no available disease-modifying drug for OA currently. This study aims to explore the role of TAK1 in OA pathogenesis and therapeutic efficiency of TAK1 inhibition for OA. The contribution of TAK1 to OA pathogenesis was invest...

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Detalles Bibliográficos
Autores principales: Cheng, Jin, Hu, Xiaoqing, Dai, Linghui, Zhang, Xin, Ren, Bo, Shi, Weili, Liu, Zhenlong, Duan, Xiaoning, Zhang, Jiying, Fu, Xin, Chen, Wenqing, Ao, Yingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041103/
https://www.ncbi.nlm.nih.gov/pubmed/27682596
http://dx.doi.org/10.1038/srep34497

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