Cell biology is different in small volumes: endogenous signals shape phenotype of primary hepatocytes cultured in microfluidic channels

The approaches for maintaining hepatocytes in vitro are aimed at recapitulating aspects of the native liver microenvironment through the use of co-cultures, surface coatings and 3D spheroids. This study highlights the effects of spatial confinement-a less studied component of the in vivo microenviro...

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Detalles Bibliográficos
Autores principales: Haque, Amranul, Gheibi, Pantea, Gao, Yandong, Foster, Elena, Son, Kyung Jin, You, Jungmok, Stybayeva, Gulnaz, Patel, Dipali, Revzin, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041105/
https://www.ncbi.nlm.nih.gov/pubmed/27681582
http://dx.doi.org/10.1038/srep33980

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