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Endophytes: A Treasure House of Bioactive Compounds of Medicinal Importance

Endophytes are an endosymbiotic group of microorganisms that colonize in plants and microbes that can be readily isolated from any microbial or plant growth medium. They act as reservoirs of novel bioactive secondary metabolites, such as alkaloids, phenolic acids, quinones, steroids, saponins, tanni...

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Autores principales: Gouda, Sushanto, Das, Gitishree, Sen, Sandeep K., Shin, Han-Seung, Patra, Jayanta Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041141/
https://www.ncbi.nlm.nih.gov/pubmed/27746767
http://dx.doi.org/10.3389/fmicb.2016.01538
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author Gouda, Sushanto
Das, Gitishree
Sen, Sandeep K.
Shin, Han-Seung
Patra, Jayanta Kumar
author_facet Gouda, Sushanto
Das, Gitishree
Sen, Sandeep K.
Shin, Han-Seung
Patra, Jayanta Kumar
author_sort Gouda, Sushanto
collection PubMed
description Endophytes are an endosymbiotic group of microorganisms that colonize in plants and microbes that can be readily isolated from any microbial or plant growth medium. They act as reservoirs of novel bioactive secondary metabolites, such as alkaloids, phenolic acids, quinones, steroids, saponins, tannins, and terpenoids that serve as a potential candidate for antimicrobial, anti-insect, anticancer and many more properties. While plant sources are being extensively explored for new chemical entities for therapeutic purposes, endophytic microbes also constitute an important source for drug discovery. This review aims to comprehend the contribution and uses of endophytes as an impending source of drugs against various forms of diseases and other possible medicinal use.
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spelling pubmed-50411412016-10-14 Endophytes: A Treasure House of Bioactive Compounds of Medicinal Importance Gouda, Sushanto Das, Gitishree Sen, Sandeep K. Shin, Han-Seung Patra, Jayanta Kumar Front Microbiol Microbiology Endophytes are an endosymbiotic group of microorganisms that colonize in plants and microbes that can be readily isolated from any microbial or plant growth medium. They act as reservoirs of novel bioactive secondary metabolites, such as alkaloids, phenolic acids, quinones, steroids, saponins, tannins, and terpenoids that serve as a potential candidate for antimicrobial, anti-insect, anticancer and many more properties. While plant sources are being extensively explored for new chemical entities for therapeutic purposes, endophytic microbes also constitute an important source for drug discovery. This review aims to comprehend the contribution and uses of endophytes as an impending source of drugs against various forms of diseases and other possible medicinal use. Frontiers Media S.A. 2016-09-29 /pmc/articles/PMC5041141/ /pubmed/27746767 http://dx.doi.org/10.3389/fmicb.2016.01538 Text en Copyright © 2016 Gouda, Das, Sen, Shin and Patra. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Gouda, Sushanto
Das, Gitishree
Sen, Sandeep K.
Shin, Han-Seung
Patra, Jayanta Kumar
Endophytes: A Treasure House of Bioactive Compounds of Medicinal Importance
title Endophytes: A Treasure House of Bioactive Compounds of Medicinal Importance
title_full Endophytes: A Treasure House of Bioactive Compounds of Medicinal Importance
title_fullStr Endophytes: A Treasure House of Bioactive Compounds of Medicinal Importance
title_full_unstemmed Endophytes: A Treasure House of Bioactive Compounds of Medicinal Importance
title_short Endophytes: A Treasure House of Bioactive Compounds of Medicinal Importance
title_sort endophytes: a treasure house of bioactive compounds of medicinal importance
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041141/
https://www.ncbi.nlm.nih.gov/pubmed/27746767
http://dx.doi.org/10.3389/fmicb.2016.01538
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