Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress

The activation of hepatic stellate cells (HSCs) plays a vital role in the progression of liver fibrosis, and the induction of HSCs apoptosis may attenuate or reverse fibrogenesis. The therapeutic effects of etoposide(VP-16), a widely used anticancer agent, on HSCs apoptosis and liver fibrosis resolu...

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Detalles Bibliográficos
Autores principales: Wang, Chen, Zhang, Feng, Cao, Yu, Zhang, Mingming, Wang, Aixiu, Xu, Mingcui, Su, Min, Zhang, Ming, Zhuge, Yuzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041150/
https://www.ncbi.nlm.nih.gov/pubmed/27680712
http://dx.doi.org/10.1038/srep34330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041150/
https://www.ncbi.nlm.nih.gov/pubmed/27680712
http://dx.doi.org/10.1038/srep34330

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